The artist has given the full amount of his £25,000 award winnings to the trust for venues, which functions to save the United Kingdom's grassroots live music spots.
He was awarded the prize on mid-October as his new release the album was declared the best record of the previous year.
He has chosen to donate the funds to the Music Venues Trust, in acknowledgment of the vital role local spots had in his initial steps.
"I personally couldn't be pursuing what I am doing today if it weren't for all the gigs I performed around the area, and further afield, when I was starting out," remarked Sam Fender. "These locations are iconic, but they are facing challenges."
From early 2023 onward, over 150 of these spaces have permanently closed – about one-sixth of the total UK scene.
Recently, major artists like the band Pulp, Coldplay, the singer Katy Perry and Ed Sheeran have all supported the MVT in its efforts to keep the scene afloat, by including a modest fee to their admission fees, which supports local stages.
Sam Fender also took part, collecting more than £100,000 on his 2024 arena tour to help 38 local spots across Britain.
The money supported venues that were confronting possible closure due to difficulties caused by water damage, fire incidents and family tragedies, as well as permit problems, legal disputes and neighbor objections.
Some locations received funding support in improving amenities and gear that helped performers and audiences.
"The notion that revenue from concerts in major spaces helps the independent spots, where it begins for artists like me, is just sensible," Sam Fender has commented.
The musician is far from the only musician to give his Mercury Prize winnings to good deeds.
In the band won the award in the year 1996 for their record Different Class, lead singer Cocker announced that the band would donate their prize money to the non-profit War Child.
That year, artist she split her bounty among several good causes, such as the NSPCC and a Sickle Cell organization.
"And I donated a thousand pounds to the center, to their gymnastics class, because I trained in gymnastics when I was a child and they required better apparatus," she explained to the media.
In recent years, they gave their winnings to the community center that developed their band, as well as other local music groups.
Also 1994 winners the group gave their prize to a multiple sclerosis charity after a acquaintance was diagnosed the disease.
"The victory was ample," stated singer Heather Small. "The cash was the bonus but we didn't need the extra, because we had the main prize. So our winning impacted the lives of others."
Last week, the MVT revealed it had saved two local spots in the South East, by placing them under local control.
One venue in that area and the other in Bristol were bought under the Own Our Venues scheme, which is funded by a national body and supporters who acquire "shares" in the buildings.